Hepcidins

Forms of hepcidin, a cationic amphipathic peptide synthesized in the liver as a prepropeptide which is first processed into prohepcidin and then into the biologically active hepcidin forms, including in human the 20-, 22-, and 25-amino acid residue peptide forms. Hepcidin acts as a homeostatic regulators of iron metabolism and also possesses antimicrobial activity.

Also Known As:

Hepcidin; Liver-Expressed Antimicrobial Peptide; Pro-Hepcidin; Prohepcidin; Antimicrobial Peptide, Liver-Expressed; Liver Expressed Antimicrobial Peptide; Peptide, Liver-Expressed Antimicrobial; Pro Hepcidin

Pharmalogical Action Categories:

Anti-Infective Agents

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Membrane Proteins: 10262
    - Pore Forming Cytotoxic Proteins
      - Antimicrobial Cationic Peptides: 426
        Hepcidins: 3084
  - Iron-Regulatory Proteins: 152
    - Hepcidins: 3084

Caroline Beaumont Selected Research

Caroline Beaumont Research Topics

Disease

Drug/Important Bio-Agent (IBA)